Causative agent 
- Eperythrozoon suis


Differential diagnosis 
- Toxoplasmosis
- Trypanosomosis
- Brucellosis
- Swine fever


1. History taking 
- Infection irrespective of grazing or inhouse
- Transmission by blood sucking flies
- Possible transmission mechanically through
  surgical instruments, needles, etc



2. Clinical examination 
- Anorexia high fever (40°C - 42°C)
- Weakness icterus
- Mild and transient in most cases



3. Microscopic examination 
- Blood smear and Giemsa-stained

4. Necrepsy 
- Pale skin and icterus (icteroanemia)
- Yellowish brown liver, enlarged spleen
- Swollen gall bladder containing thick bile
- Jaundice in every organ
- Occasional petechial hemorrhage on the gall
  bladder mucosa

5. Histopathological observation 
- Fatty change, centrilobular degeneration and
  necrosis of liver
- Hyperplasia of bone marrow
- Hemosiderosis in liver and spleen
- Activation of reticuloendothelial system

Control and treatment 
- Control measures against blood sucking flies
- Always use sterile instruments
- Treatment with oxytetracycline