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60. Toxoplasmosis

Causative agent 
- Toxoplasma gondii


Differential diagnosis 
- Brucellosis
- Aujeszky's disease
- Parvovirus infection
- Leptospirosis



1. History taking 
- High prevalence in breeding pigs
- Low conception rate and abortion
- Presence of cats, rodents and birds in stall



2. Clinical examination 
- Young pigs high fever, pneumonia
- Adult pig weakness, cough, tremor but no fever 
- Pregnant sow :  abortion, mummified fetus
 and stillbirths 



3. Serological tests 
- IFAT
- Latex agglutination test
- Modified agglutination test

4. Necropsy 
- Hydrothorax
- Pericarditis
- Enlargement of lymph nodes, spleen



5. Histopathological observation 
- Necrotic foci in the lung, liver and kidney
- Fibrinous pneumonia
- Lymphadenitis
- Tachyzoites found in tissue sections of lung,
  liver and brain
- Encephalitis



6. Experimental animal inoculation 
- Inoculation of tissue (lung, brain, liver, heart
  and fetus) into mice



Control and treatment 
- Isolation of infected animals
- Keep away from birds, rats and cats
- Avoid to feed pigs with uncooked garbage


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