Causative agent 
- Burkholderia (Pseudomonas) pseudomallei


Differential diagnosis 
- Tuberculosis
- Actinobacillosis
- Actinomyces pyogenes infection
- Corynebacterium pseudotuberculosis
  infection

1. History taking 
- High prevalence in wet season after heavy
  rainfall or flood with high humidity and
  temperature
- Transmission from contaminated
  environment, through wounds or
  cutaneous abrasion, inhalation or
  ingestion
- Outbreak originates from soilborn infection
  and the organism can survive for
  many months in soil and water
- Predisposed by starvation, parturition,
  abortion or other stresses
- Host : ruminants, horse, pig, pets various
  wild animals and man


2. Clinical examination 
- Loss of body weight, weakness, anorexia
  and recumbency
- Nervous signs : abnormal gait, posterior
  paresis, walk in circle or blindness
- Respiratory signs : coughing, occular or
  nasal discharge
- Mastitis, metritis, orchitis, arthritis or
  abortion

3. Necropsy 
- Multiple abscesses (size 0.1-5 cm) in lung,
  liver, spleen, kidney, uterus, udder lymph
  nodes trachea and joints
- Abscesses surrounded by thick wall and
  filled with caseous greenish yellow pus
- Large abscesses replace testicular tissue
  causing distention of scrotal sac
- Lung, consolidation with reddish
  atelectasis