Causative agents
- Cryptosporidium parvum
Differential diagnosis
- Coccidiosis
- Salmonellosis
- Enteroxigenic E. coli
- Rotavirus infection
- Coronavirus infection
1. History taking
- Common in neonatal calves, primarily from 5
to 15 days of age
2. Clinical examination
- Watery diarrhea
- Occasional anorexia
- Weight loss
- Apathy
- Tenesmus
- Dehydration, weakness
3. Fecal examination
- Fecal smear : acid fast staining
- Fecal flotation
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4. Necropsy
- Generalized infection of the gastrointestinal
tract
- Enteritis
- Moderate to severe mucosal changes
5. Histopathological observation
- Blunting and loss of intestinal tract villi
- Crypt hyperplasia, replacement of mature
coating epithelial cells with immature cells
- Extensive infiltration of the lamina propria
with inflammatory cells
- Presence of large number of Cryptosporidia in
sections of freshly fixed lower small intestine
Control and treatment
- Supportive therapy for dehydration
- Killing the occysts in the environment with
5% ammonia solution
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