Causative agents
- Fasciola gigantica
Differential diagnosis
- Ketosis
- Paramphistomiasis
- Amyloidosis
- Paratuberculosis
1. History taking
- Known endemic area
- No treatment for liver fluke
- Presence of snail colony
- Relation between pasture, paddock, sewerage
and snail colony
- Source of grass feed
2. Clinical examination
- Emaciation, dullness, weakness
- Anemia
- Edema
- Diarrhea
- Milk reduction
3. Fecal examination
- Sedimentation methods :
- Simple sedimentation
- Formalin-ether sedimentation technique
- Beads technique
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4. Serological test
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5. Necropsy
- Acute fasciolosis : hemorrhage and immature
worms in liver parenchyma
- Chronic fasciolosis : thickness of bile ducts,
fibrosis, calcification, adult worms in gall
bladder and bile duct
6. Histopathological observation
- Servere fibrosis in the perilobular connective
tissue of liver
- Neutrophils, eosinophils and lymphocytes
infiltration
- Hyperplasia of gall bladder epithelial mucosa
Control and treatment
- Snail control
- good drainage
- biological control
- molluscicide
- Environmental control
- good drainage
- pasture burning
- pipe-drinking water
- Chemotherapy
- effective anthelmintics
- strategic control program
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