Causative agent
- PED virus, family Coronaviridae


Differential diagnosis
- Transmissible gastroenteritis
- Hemagglutinating encephalomyelitis virus infection


1. Epidemiology
- PED virus is transmitted by fecal-oral route
- Fattening pigs are more susceptible to virus
  infection and 100% morbidity during an outbreak
- The progress of the infection occurs at a slower
  rate with longer incubation period than TGE virus
  infection


2. Clinical examination
- Anorexia and depress
- Watery diarrhea and abdominal pain
- PED is more severe than TGE


3. Necropsy
- Small intestine distended with yellowish fluid


4. Histophathological observation
- Vacuolation and exfoliation of enterocytes on the
  small intestinal villi at the early infection and later
  shortening of villi occurs

5. Serological test
Specimens : acute and convalescent paired sera
Method      : SN test


6. Antigen dectection
Specimens : small intestine
Method      : FA test on cryostat section


7. Virus isolation
Specimens : intestine and fecal contents
Method      : Vero cell culture inoculation and CPE
observation


8. Virus identification
- FA test


Control
- Sanitation and management
- Prevention of introduction of the virus into farm